5,6,7,8-四氢-1,6-萘啶合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in acetic acid T=50 - 60°C;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 7 p. 2522 - 2529
反应条件
palladium 10 on activated carbon; hydrogen in ethanol P=2844.39 Torr; 3.5 h;
参考文献
WO2013/55984 A1, ;
Paragraph 00457 ;
反应条件
1: Et3N; pyridinium acetate / 22 h / 120 °C 2: H2; AcOH / Pd/C / 2 h / 50 - 60 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 21 p. 5167 - 5182
反应条件
1: 981 mg / aq. NaOH / toluene / 0.17 h 2: 98 percent / m-chloroperbenzoic acid / CH2Cl2 / 0.5 h / 0 °C 3: 88 percent / N,N-dimethylcarbamyl chloride / CH2Cl2 / 41 h / 20 °C View Scheme
参考文献
Haginoya, Noriyasu; Kobayashi, Syozo; Komoriya, Satoshi; Yoshino, Toshiharu; Suzuki, Makoto; Shimada, Takashi; Watanabe, Kengo; Hirokawa, Yumiko; Furugori, Taketoshi; Nagahara, Takayasu
Journal of Medicinal Chemistry, 2004 , vol. 47, # 21 p. 5167 - 5182
