5-甲基-2(3H)-苯并噻唑酮腙合成路线 （共 3 条）
反应条件
ethanol; hydrazine hydrate
T=80°C; 5 h;
参考文献
Easmon; Heinisch; Hofmann; Langer; Grunicke; Fink; Puerstinger
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 397 - 408
反应条件
1: 65 percent / aq. NaOH / 3 h / Ambient temperature
2: 97 percent / NH2NH2*H2O, EtOH / 5 h / 80 °C
View Scheme
参考文献
Easmon; Heinisch; Hofmann; Langer; Grunicke; Fink; Puerstinger
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 397 - 408
反应条件
1: 1.) NaH / 1.) diethylene glycol monoethyl ether, room temperature, 30 min, 2.) 140 deg C, 5-6 h
2: 65 percent / aq. NaOH / 3 h / Ambient temperature
3: 97 percent / NH2NH2*H2O, EtOH / 5 h / 80 °C
View Scheme
参考文献
Easmon; Heinisch; Hofmann; Langer; Grunicke; Fink; Puerstinger
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 397 - 408
