7-氧代胆甾-5-烯-3-beta-基乙酸酯合成路线 （共 77 条）
反应条件
1: aluminium isopropylate; isopropyl alcohol / Behandeln der Reaktionsloesung mit wss. KOH bei Raumtemperatur; Reinigung ueber das Dibenzoyl-Derivat 2: pyridine 3: Hydrolyse des Reaktionsprodukts View Scheme
参考文献
Windaus; Lettre; Schenck
Justus Liebigs Annalen der Chemie, 1935 , vol. 520, p. 98,104
反应条件
1: aluminium isopropylate; isopropyl alcohol / Behandeln der Reaktionsloesung mit wss. KOH bei Raumtemperatur; Reinigung ueber das Dibenzoyl-Derivat 2: pyridine 3: Hydrolyse des Reaktionsprodukts 4: sodium; ethanol; propanol-(1) View Scheme
参考文献
Buser
Helvetica Chimica Acta, 1947 , vol. 30, p. 1379,1386
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=65°C; 2 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 19, # 6 p. 509 - 510
参考文献
Journal of the American Chemical Society, , vol. 71, p. 2226,2229
反应条件
anschliessenden Behandeln mit wss.KOH;
参考文献
Helvetica Chimica Acta, , vol. 30, p. 1379,1386
Justus Liebigs Annalen der Chemie, , vol. 520, p. 98,104
US2376817 , ;
US2098984 , ;
US2098985 , ;
DE701601 , ;
DRP/DRBP Org.Chem.
反应条件
sodium tetrahydroborate; cerium (III) chloride heptahydrate in tetrahydrofuran; methanol T=20°C; 0.25 h;
参考文献
Carvalho, Joao F. S.; Silva, M. Manuel Cruz; Moreira, Joao N.; Simoes, Sergio; Sa E Melo, M. Luisa
Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7632 - 7638
反应条件
sodium tetrahydroborate in 1,4-dioxane 5 h; other time (22 h), various solvents (n-PrOH, C6H6-EtOH); stereospecific reduction of 7-oxo group in 3β-acetoxycholest-5-en-7-one; Product distribution;
参考文献
Synthetic Communications, , vol. 19, # 3and4 p. 439 - 442
