3-(4-硝基苯基)丙烷合成路线 （共 21 条）
反应条件
(S)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dichloromethane T=20°C; 4 h; stereoselective reaction;
参考文献
Zhang, Shilei; Xie, Hexin; Song, Aiguo; Wu, Deyan; Zhu, Jin; Zhao, Sihan; Li, Jian; Yu, Xinhong; Wang, Wei
Science China Chemistry, 2011 , vol. 54, # 12 p. 1932 - 1936
参考文献
Ingold; Piggott
Journal of the Chemical Society, 1923 , vol. 123, p. 1482,1508
反应条件
oxygen; palladium diacetate; 2-methoxy-phenylamine in dimethyl sulfoxide T=60°C; direct Saegusa oxidation reaction; P=760.051 Torr; 18 h;
参考文献
Liu, Jie; Zhu, Jin; Jiang, Hualiang; Wang, Wei; Li, Jian
Chemistry - An Asian Journal, 2009 , vol. 4, # 11 p. 1712 - 1716
参考文献
Ingold; Piggott
Journal of the Chemical Society, 1923 , vol. 123, p. 1482,1508
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; (Bn2NH2)(OCOCF3) in tetrahydrofuran
T=20°C; 5 h;
参考文献
Yang, Jung Woon; Hechavarria Fonseca, Maria T.; List, Benjamin
Angewandte Chemie - International Edition, 2004 , vol. 43, # 48 p. 6660 - 6662
反应条件
1: With phenyl silane; triethylamine in tetrahydrofuran
T=20°C; 2 h; Inert atmosphere;
2: With water
0.25 h; Inert atmosphere;
参考文献
Frost, Christopher G.; Hartley, Benjamin C.
Journal of Organic Chemistry, 2009 , vol. 74, # 9 p. 3599 - 3602
反应条件
1: With phenyl silane; 4-methylmorpholine N-oxide; hexacarbonyl molybdenum in tetrahydrofuran
T=80°C; 16 h;
2: With water in tetrahydrofuran
T=20°C; 0.25 h; Further stages.;
参考文献
Frost, Christopher G.; Hartley, Benjamin C.
Journal of Organic Chemistry, 2009 , vol. 74, # 9 p. 3599 - 3602
反应条件
tetrabutyl-ammonium chloride; sodium hydrogencarbonate; palladium diacetate in DMF (N,N-dimethyl-formamide)
T=35°C; 30 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/54202 A1, 2005 ;
Location in patent: Page/Page column 43 ;
WO 2005/054202 A1
反应条件
hydrogen; tin(ll) chloride; ((2S,4S)-N-(tert-butoxycarbonyl)-4-(diphenylphosphino)-2-{(diphenylphosphino)methyl}pyrrolidine)PtCl2 in benzene
T=60°C; P=137044 Torr; 8 h; Yield given. Yields of byproduct given;
参考文献
Parrinello, Giovanni; Stille, J. K.
Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7122 - 7127
反应条件
tetrabutyl-ammonium chloride; oxygen; palladium diacetate; sodium hydrogencarbonate in dimethyl sulfoxide; N,N-dimethyl-formamide
T=60°C; Heck-Saegusa reaction; P=760.051 Torr; 5 h;
参考文献
Liu, Jie; Zhu, Jin; Jiang, Hualiang; Wang, Wei; Li, Jian
Chemical Communications, 2010 , vol. 46, # 3 p. 415 - 417
