4,5,6,7-四氢-1H-吲哚-2-甲醛合成路线 （共 7 条）
反应条件
1: With trichlorophosphate T=20°C; 13.33 h; Inert atmosphereCooling with ice; 2: With sodium hydroxide in water 0.666667 h;
参考文献
THE JOHNS HOPKINS UNIVERSITY; THE SCRIPPS RESEARCH INSTITUTE; ZACK, Donald, Jeffrey; BANNISTER, Thomas; VOJKOVSKY, Tomas; YANG, Zhiyong; BERLINICKE, Cynthia
Patent: WO2011/119777 A2, 2011 ;
Location in patent: Page/Page column 35-36 ;
WO 2011/119777 A2
反应条件
1: With trichlorophosphate in 1,2-dichloro-ethane Vilsmeier-Haack reaction; 0.25 h; Heating; 2: With sodium acetate 0.25 h; Heating;
参考文献
Tetrahedron Letters, , vol. 47, # 22 p. 3693 - 3696
参考文献
Tetrahedron Letters, , vol. 26, # 50 p. 6183 - 6184
反应条件
1: 50 percent / formic acid / benzene / Heating 2: 18 percent / tetrahydrofuran / 440 °C / 15 Torr / other cyclic enaminoesters View Scheme
参考文献
Bulletin de la Societe Chimique de France, , # 5 p. 644 - 649
反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 26.5 h / 75 - 80 °C / Reflux; Inert atmosphere 1.2: 0.5 h 2.1: trichlorophosphate / 13.33 h / 20 °C / Inert atmosphere; Cooling with ice 2.2: 0.67 h View Scheme
参考文献
WO2011/119777 A2, ;
WO 2011/119777 A2
反应条件
in tetrahydrofuran T=440°C; P=15 Torr;
参考文献
Bulletin de la Societe Chimique de France, , # 5 p. 644 - 649
反应条件
2: 17 percent / 420 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 50 p. 6183 - 6184
