4-(苯并[d][1,3]二氧代l-5-甲基)二氢呋喃-2(3H)-酮合成路线 （共 23 条）
反应条件
lithium hexamethyldisilazane in hexane; benzene T=-20°C; 0.0833333 h; Yield given. Yields of byproduct given;
参考文献
Trazzi, Giordano; Andre, Marcelo Fabiano; Coelho, Fernando
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 12 p. 2327 - 2339
反应条件
1: hexamethyldisilylamidure de lithium / benzene; hexane / 0.08 h / -20 °C 2: 77 percent / Jones / acetone / 0.25 h 3: 10 percent / NaBH4 / CH2Cl2; methanol / 0.25 h / 0 - 20 °C View Scheme
参考文献
Robin, Jean-Pierre; Dhal, Robert; Brown, Eric
Tetrahedron, 1982 , vol. 38, # 24 p. 3667 - 3671
反应条件
1: NBS, BPO / CCl4 / 1.5 h / Heating 2: 51 percent / CrO3, pyridine / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Ishiguro; Mizuguchi; Tomioka; Koga
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 2 p. 609 - 617
反应条件
Candida antarctica lipase; dihydrogen peroxide; n-tetradecanoic acid in toluene
144 h;
参考文献
Lemoult, Stephanie C.; Richardson, Paul F.; Roberts, Stanley M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 2 p. 89 - 92
反应条件
hydrogen; Ra-Ni T4
P=75.0075 Torr; 2 h;
参考文献
Kamlage; Sefkow; Pool-Zobel; Peter
Chemical Communications, 2001 , # 4 p. 331 - 332
反应条件
sodium tetrahydroborate; calcium chloride in ethanol
1.) -5 deg C, 2 h, 2.) RT, 4 h;
参考文献
Banerji, Julie; Das, Biswanath
Heterocycles, 1985 , vol. 23, # 3 p. 661 - 665
反应条件
hydrogen; palladium on activated charcoal
P=760 Torr;
参考文献
Morimoto, Toshiaki; Nagai, Hazuki; Achiwa, Kazuo
Synthetic Communications, 2005 , vol. 35, # 6 p. 857 - 865
反应条件
1: acetic acid; zinc / 0 - 70 °C
2: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 18 h / 35 °C
View Scheme
参考文献
Zhou, Lin; Liu, Xiaohua; Ji, Jie; Zhang, Yuheng; Hu, Xiaolei; Lin, Lili; Feng, Xiaoming
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17023 - 17026,4
反应条件
1: trichlorophosphate / diethyl ether / |Reflux
2: acetic acid; zinc / 0 - 70 °C
3: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 18 h / 35 °C
View Scheme
参考文献
Zhou, Lin; Liu, Xiaohua; Ji, Jie; Zhang, Yuheng; Hu, Xiaolei; Lin, Lili; Feng, Xiaoming
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17023 - 17026,4
反应条件
C23H21ClNPRu; potassium tert-butylate in acetone
T=30°C; 1 h; regioselective reaction;
参考文献
Ito, Masato; Shiibashi, Akira; Ikariya, Takao
Chemical Communications, 2011 , vol. 47, # 7 p. 2134 - 2136
