2-甲酰基-3-氧代丙酸乙酯合成路线 （共 23 条）
反应条件
sodium hydride in diethyl ether T=0 - 20°C; 15 h;
参考文献
EP1364946 A1, ;
Page/Page column 196 ;
反应条件
1: formic acid ethyl ester With sodium hydride in diethyl ether T=0°C; Argon atmosphere; 2: methyl 3,3-dimethoxy-propanoate T=0 - 20°C; 1.66667 h; Argon atmosphere; 3: With water
参考文献
WO2006/97691 A1, ;
Page/Page column 32 ;
WO 2006/097691 A1
反应条件
sodium hydride 1.) ether; 2.) ether, 5 deg C, 10 h; room temp., overnight; Yield given. Multistep reaction;
参考文献
Synthesis, , # 5 p. 400 - 402
参考文献
Tetrahedron Letters, , vol. 22, # 36 p. 3451 - 3454
反应条件
1: 1.) (C2H5)3N / 1.) ether, room temp., 1 h; 2.) DMF, -20 deg C -> room temp.; 3 h 2: pyridine / dimethylformamide / 10 h / 80 °C View Scheme
参考文献
Torii, Sigeru; Inokuchi, Tsutomu; Kubota, Minoru
Synthesis, 1986 , # 5 p. 400 - 402
反应条件
1: 1.) (C2H5)3N / 1.) ether, room temp., 1 h; 2.) DMF, -20 deg C -> room temp.; 3 h 2: pyridine / dimethylformamide / 15 h / 80 °C View Scheme
参考文献
Torii, Sigeru; Inokuchi, Tsutomu; Kubota, Minoru
Synthesis, 1986 , # 5 p. 400 - 402
反应条件
in ethanol T=0 - 20°C; 24 h;
参考文献
Holzer, Wolfgang; Seiringer, Gertrud
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 865 - 872
反应条件
1: 1.) (C2H5)3N / 1.) ether, room temp., 1 h; 2.) DMF, -20 deg C -> room temp.; 3 h 2: pyridine / dimethylformamide / 10 h / 80 °C View Scheme
参考文献
Torii, Sigeru; Inokuchi, Tsutomu; Kubota, Minoru
Synthesis, 1986 , # 5 p. 400 - 402
反应条件
hydraziniumdihydrochloride in ethanol T=0 - 20°C; 32 h;
参考文献
Allin, Steven M.; Barton, William R.S.; Russell Bowman; Bridge (nee Mann), Emma; Elsegood, Mark R.J.; McInally, Tom; McKee, Vickie
Tetrahedron, 2008 , vol. 64, # 33 p. 7745 - 7758
反应条件
sodium hydroxide anschliessend Behandeln mit Essigsaeure und Anilin;
参考文献
Panizzi
Gazzetta Chimica Italiana, 1946 , vol. 76, p. 44,53
