(1,1-二氧代-1H-苯并[d]异噻唑-3-基磺酰基)-乙腈合成路线 （共 4 条）
反应条件
ammonia in methanol 0.5 h;
参考文献
Rode, Haridas B.; Sprang; Besch; Loose; Otto, Hans-Hartwig
Pharmazie, 2005 , vol. 60, # 10 p. 723 - 731
反应条件
1: thiosaccharin With sodium hydride in N,N-dimethyl-formamide
T=0°C; 0.5 h;
2: chloroacetonitrile in N,N-dimethyl-formamide
10 h; Heating;
参考文献
Rode, Haridas B.; Sprang; Besch; Loose; Otto, Hans-Hartwig
Pharmazie, 2005 , vol. 60, # 10 p. 723 - 731
反应条件
in N,N-dimethyl-formamide
3.5 h; Ambient temperature;
参考文献
Inomata, Katsuhiko; Yamada, Hiroyuki; Kotake, Hiroshi
Chemistry Letters, 1981 , p. 1457 - 1458
Title/Abstract Full Text Show Details
Yamada, Hiroyuki; Kinoshita, Hideki; Inomata, Katsuhiko; Kotake, Hiroshi
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 3 p. 949 - 950
反应条件
1.1: 75 percent / P2S5 / 50 - 170 °C
2.1: NaH / dimethylformamide / 0.5 h / 0 °C
2.2: 50 percent / dimethylformamide / 10 h / Heating
View Scheme
参考文献
Rode, Haridas B.; Sprang; Besch; Loose; Otto, Hans-Hartwig
Pharmazie, 2005 , vol. 60, # 10 p. 723 - 731
