1: n-butyllithium; 1-bromo-4-(1,1-dimethylethyl)benzene in tetrahydrofuran; hexanes T=-78°C; 1 h; 2: oxalic acid diethyl ester in tetrahydrofuran; hexanes T=-78°C; 1 h;

1: oxalic acid monoethyl ester chloride With AlCl3, aluminium chloride in dichloromethane T=20°C; Friedel Crafts acylation; Inert atmosphere; 2: tert-butyl benzene in dichloromethane T=5 - 20°C; Friedel Crafts acylation; 2 h; Inert atmosphere; regioselective reaction;

1: 1-bromo-4-(1,1-dimethylethyl)benzene With iodine; magnesium in tetrahydrofuran Inert atmosphere; 2: oxalic acid diethyl ester in tetrahydrofuran T=-78 - 20°C; 14 h; Inert atmosphere;

chromium(VI) oxide in acetic acid Heating;

in tetrahydrofuran T=-78°C; 1 h; Schlenk techniqueInert atmosphere;