3-(2-苯氧基乙氧基)苯胺合成路线 （共 5 条）
反应条件
1: toluene / 6 h / Heating 2: diphenyl ether / 0.13 h / 255 - 256 °C 3: 20percent aq. NaOH / 0.5 h / Heating View Scheme
参考文献
Coats; Shah; Milstein; Genther; Nene; Roesener; Schmidt; Pleiss; Wagner; Baker
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 57 - 63
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal
参考文献
Baker; Lourens
Journal of pharmaceutical sciences, 1967 , vol. 56, # 7 p. 871 - 875
反应条件
1: 1.) sodium / 1.) ethanol, RT, 0.5 h, 2.) ethanol, reflux, 21 h
2: SnCl2*2H2O, concd. HCl / ethanol / Heating
View Scheme
参考文献
Coats; Shah; Milstein; Genther; Nene; Roesener; Schmidt; Pleiss; Wagner; Baker
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 57 - 63
反应条件
1: base
2: 1.) sodium / 1.) ethanol, RT, 0.5 h, 2.) ethanol, reflux, 21 h
3: SnCl2*2H2O, concd. HCl / ethanol / Heating
View Scheme
参考文献
Coats; Shah; Milstein; Genther; Nene; Roesener; Schmidt; Pleiss; Wagner; Baker
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 57 - 63
反应条件
1: NaOMe
2: H2, aq. HCl / Pd-C
View Scheme
参考文献
Baker; Lourens
Journal of pharmaceutical sciences, 1967 , vol. 56, # 7 p. 871 - 875
