N-(苄氧基)氨基甲酸叔丁酯合成路线 （共 15 条）
反应条件
sodium hydrogencarbonate in dichloromethane; water T=0°C; 3 h;
参考文献
Bongim; Cardillo; Gentilucci; Tomasini
Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9148 - 9159
反应条件
in tetrahydrofuran T=20°C; 20 h;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); GUICHOU, Jean-Francois; COLLIANDRE, Lionel; AHMED-BELKACEM, Hakim; PAWLOTSKY, Jean-Michel
Patent: WO2011/76784 A2, 2011 ;
Location in patent: Page/Page column 96-97 ;
反应条件
triethylamine in tetrahydrofuran; water T=20°C;
参考文献
Kadi, Nadia; Arbache, Simon; Song, Lijiang; Oves-Costales, Daniel; Challis, Gregory L.
Journal of the American Chemical Society, 2008 , vol. 130, # 32 p. 10458 - 10459
反应条件
in 1,4-dioxane; water
参考文献
Ortho Pharmaceutical Corporation
Patent: US5066658 A1, 1991 ;
US 5066658 A
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water 2 h; Ambient temperature;
参考文献
Sulsky, Richard; Demers, James P.
Tetrahedron Letters, 1989 , vol. 30, p. 31 - 34
反应条件
1: benzyl alcohol With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; Metallation; 2: t-butyl 3-(trichloromethyl)-1,2-oxaziridine-2-carboxylate in tetrahydrofuran T=-78 - 20°C; Substitution; Further stages.;
参考文献
Chemical Communications, , # 11 p. 975 - 976
反应条件
triphenylphosphine; diethylazodicarboxylate in toluene 1.) -20 deg C, 1 h, 2.) room temperature, 1 h;
参考文献
Oehler, Elisabeth; Kanzler, Silvia
Phosphorus, Sulfur and Silicon and Related Elements, 1996 , vol. 112, # 1-4 p. 71 - 90
反应条件
1: sodium hydride 2: trifluoroacetic acid View Scheme
参考文献
Jobbins, Maria O.; Miller, Marvin J.
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1620 - 1625
反应条件
1: 98 percent / NaH; NaI / dimethylformamide 2: 91 percent / H2; NH3 / Raney Ni / methanol View Scheme
参考文献
Bergeron, R. J.; McManis, J. S.
Tetrahedron, 1989 , vol. 45, # 16 p. 4939 - 4944
反应条件
1: Nα-tert-Butyloxycarbonyl-O-benzylhydroxylamine With sodium hydride; sodium iodide in DMF (N,N-dimethyl-formamide) T=20°C; 0.25 h; 2: 4-chloro-valeronitrile in DMF (N,N-dimethyl-formamide) T=85°C; 3.5 h;
参考文献
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA
Patent: WO2004/58756 A1, 2004 ;
Location in patent: Page 38, 39 ;
