N3-苄基-吡啶-2,3-二胺合成路线 （共 11 条）
反应条件
BrettPhos Palladacycle; lithium hexamethyldisilazane in tetrahydrofuran T=65°C; 12 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 13, # 8 p. 1984 - 1987
反应条件
triethylamine in ethanol
反应条件
hydrogenchloride; iron in ethanol; water 3 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 5 p. 529 - 535
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 5 p. 639 - 645
反应条件
sodium tetrahydroborate; 3 A molecular sieve in ethanol Ambient temperature; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 7 p. 876 - 892
反应条件
1: 3 A molecular sieves / ethanol / 72 h / Ambient temperature 2: sodium borohydride, 3A molecular sieves / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 7 p. 876 - 892
反应条件
1: 3 A molecular sieves / ethanol / 72 h / Ambient temperature 2: sodium borohydride, 3A molecular sieves / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 7 p. 876 - 892
反应条件
1: 90 percent / CHCl3 / 2 h / 110 °C 2: 75 percent / iron, conc. hydrochloric acid / ethanol; H2O / 3 h / Heating View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 5 p. 529 - 535
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 5 p. 639 - 645
反应条件
1: 90 percent / CHCl3 / 2 h / 110 °C 2: 75 percent / iron, conc. hydrochloric acid / ethanol; H2O / 3 h / Heating View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 5 p. 529 - 535
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 5 p. 639 - 645
反应条件
1: in tetrahydrofuran 4 h; Molecular sieveReflux; 2: With sodium tetrahydroborate in tetrahydrofuran; ethanol 20 h; Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 57, p. 311 - 322
反应条件
sodium tetrahydroborate; 4 A molecular sieve 1.) C6H6, reflux, 3 h; r.t., 20 h, 2.) EtOH, reflux, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 60, # 4 p. 960 - 965
