(2R,3R,4S,5R,6R)-5-氟-2-(羟基甲基)-6-甲氧基四氢吡喃-3,4-二醇合成路线 （共 6 条）
反应条件
1: DMSO / acetic anhydride
2: lithium aluminum hydride
3: pyridine
4: 50 percent / tetraethylammonium fluoride / acetonitrile / 0.83 h / 50 °C
5: acetic acid
View Scheme
参考文献
Haradahira, Terushi; Maeda, Minoru; Yano, Yuji; Kojima, Masaharu
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3317 - 3319
反应条件
1: lithium aluminum hydride
2: pyridine
3: 50 percent / tetraethylammonium fluoride / acetonitrile / 0.83 h / 50 °C
4: acetic acid
View Scheme
参考文献
Haradahira, Terushi; Maeda, Minoru; Yano, Yuji; Kojima, Masaharu
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3317 - 3319
反应条件
1: 50 percent / tetraethylammonium fluoride / acetonitrile / 0.83 h / 50 °C
2: acetic acid
View Scheme
参考文献
Haradahira, Terushi; Maeda, Minoru; Yano, Yuji; Kojima, Masaharu
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3317 - 3319
反应条件
1: pyridine
2: 50 percent / tetraethylammonium fluoride / acetonitrile / 0.83 h / 50 °C
3: acetic acid
View Scheme
参考文献
Haradahira, Terushi; Maeda, Minoru; Yano, Yuji; Kojima, Masaharu
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3317 - 3319
反应条件
hydrogenchloride
2 h; Heating;
参考文献
Ittah; Glaudemans
Carbohydrate research, 1981 , vol. 95, # 2 p. 189 - 194
参考文献
Haradahira, Terushi; Maeda, Minoru; Yano, Yuji; Kojima, Masaharu
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3317 - 3319
