6-溴-1,4-二氢-4-氧代-3-喹啉羧酸乙酯合成路线 (共 7 条)
反应条件
sodium hydroxide 1 h; Heating;
参考文献
Gaeta, Alessandra; Woodcraft, John; Plant, Stuart; Goggi, Julian; Jones, Paul; Battle, Mark; Trigg, William; Luthra, Sajinder K.; Glaser, Matthias
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4649 - 4652
反应条件
sodium hydroxide 1 h; Heating;
参考文献
Gaeta, Alessandra; Woodcraft, John; Plant, Stuart; Goggi, Julian; Jones, Paul; Battle, Mark; Trigg, William; Luthra, Sajinder K.; Glaser, Matthias
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4649 - 4652
反应条件
thionyl chloride; N,N-dimethyl-formamide 2 h; Reflux;
参考文献
Lopez Rivilli, Marisa J.; Moyano, Elizabeth L.; Yranzo, Gloria I.
Tetrahedron Letters, 2010 , vol. 51, # 3 p. 478 - 481
反应条件
in diphenylether
T=250°C; 0.0833333 h; microwave irradiation;
参考文献
GE HEALTHCARE LIMITED
Patent: WO2009/40377 A2, 2009 ;
Location in patent: Page/Page column 19 ;
反应条件
1: ethanol / Reflux
2: diphenylether / Reflux
View Scheme
参考文献
Reis, Raisa Da R.; Azevedo, Elisa C.; De Souza, Maria Cecilia B.V.; Ferreira, Vitor Francisco; Montenegro, Raquel C.; Araujo, Ana Jersia; Pessoa, Claudia; Costa-Lotufo, Leticia V.; De Moraes, Manoel O.; Filho, Jose D.B.M.; De Souza, Alessandra M.T.; De Carvalho, Natasha C.; Castro, Helena C.; Rodrigues, Carlos R.; Vasconcelos, Thatyana R.A.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1448 - 1452
反应条件
1: ethanol / Reflux
2: diphenylether / Reflux
View Scheme
参考文献
Reis, Raisa Da R.; Azevedo, Elisa C.; De Souza, Maria Cecilia B.V.; Ferreira, Vitor Francisco; Montenegro, Raquel C.; Araujo, Ana Jersia; Pessoa, Claudia; Costa-Lotufo, Leticia V.; De Moraes, Manoel O.; Filho, Jose D.B.M.; De Souza, Alessandra M.T.; De Carvalho, Natasha C.; Castro, Helena C.; Rodrigues, Carlos R.; Vasconcelos, Thatyana R.A.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1448 - 1452
反应条件
Gould-Jacob reaction; 0.233333 h; Irradiation;
参考文献
Dave, Chaitanya G.; Joshipura, Hardik M.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 3 p. 650 - 652