lithium hydroxide; dihydrogen peroxide in tetrahydrofuran T=0°C; Ring cleavage; Hydrolysis; 2 h;
参考文献
Harding, John R.; Hughes, Rachael A.; Kelly, Nicholas M.; Sutherland, Andrew; Willis, Christine L.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3406 - 3416
1: 91 percent / aq. LiOH; H2O2 / tetrahydrofuran / 2 h / 0 °C
2: DMAP; EDCI / CH2Cl2 / 16 h / 20 °C
3: O3 / methanol; CH2Cl2 / -78 - 20 °C
4: lipase from Candida rugosa / ethanol; aq. phosphate buffer / 5 h / 20 °C / pH 7.0 - 8.5
View Scheme
参考文献
Harding, John R.; Hughes, Rachael A.; Kelly, Nicholas M.; Sutherland, Andrew; Willis, Christine L.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3406 - 3416
