4-3,5-二甲基-4H-1,2,4-三氮唑-4-哌啶合成路线 （共 4 条）
反应条件
palladium hydroxide on carbon; hydrogen T=40°C; P=2068.65 Torr; 12 h;
参考文献
ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; WANG, Xueqing; MEYER, Michael; YAO, Betty; GUO, Tao; WEI, Guo Ping,Robert; WANG, Lijuan, Jane
Patent: WO2013/10453 A1, 2013 ;
Location in patent: Page/Page column 112 ;
反应条件
1: pyridine; trichlorophosphate / chloroform / 12 h / 0 - 20 °C 2: chloroform / 5 h / |Reflux 3: hydrogenchloride / 12 h / |Reflux 4: hydrogen; palladium hydroxide on carbon / 12 h / 40 °C / 2068.65 Torr View Scheme
反应条件
1: triethylamine / 12 h / 0 - 20 °C 2: pyridine; trichlorophosphate / chloroform / 12 h / 0 - 20 °C 3: chloroform / 5 h / |Reflux 4: hydrogenchloride / 12 h / |Reflux 5: hydrogen; palladium hydroxide on carbon / 12 h / 40 °C / 2068.65 Torr View Scheme
反应条件
1: hydrogenchloride / 12 h / |Reflux 2: hydrogen; palladium hydroxide on carbon / 12 h / 40 °C / 2068.65 Torr View Scheme
