4-羟基-1-(4-硝基苯基)哌啶合成路线 （共 4 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=85°C; 1 h;
参考文献
SHIONOGI and CO., LTD.
Patent: EP1988077 A1, 2008 ;
Location in patent: Page/Page column 64 ;
反应条件
potassium carbonate in N,N-dimethyl acetamide T=130°C; 3 h;
参考文献
TAIHO PHARMACEUTICAL CO., LTD.
Patent: US2011/319413 A1, 2011 ;
Location in patent: Page/Page column 11 ;
US 20110319413 A1
反应条件
in ethanol; water Beauveria sulfurescens ATCC 7159;
参考文献
Floyd, Nicholas; Munyemana, Francois; Roberts, Stanley M.; Willetts, Andrew J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 8 p. 881 - 882
反应条件
pyridine; dimethyl sulfoxide; dicyclohexyl-carbodiimide; trifluoroacetic acid in benzene ice-water bath temp. - room temp., overnight;
参考文献
Taylor, Edward C.; Skotnicki, Jerauld S.
Synthesis, 1981 , # 8 p. 606 - 608
