2-氯-1-(6-甲氧基吲哚啉-1-基)乙酮合成路线 (共 3 条)
反应条件
potassium carbonate in dichloromethane
T=20°C; 6 h;
参考文献
Vermeulen, Erik S; van Smeden, Marjan; Schmidt, Anne W; Sprouse, Jeffrey S; Wikstroem, Hakan V; Grol, Cor J
Journal of medicinal chemistry, 2004 , vol. 47, # 22 p. 5451 - 5466
反应条件
1: 97 percent / NaCNBH3; glacial acetic acid / 3 h / 20 °C
2: 88 percent / K2CO3 / CH2Cl2 / 6 h / 20 °C
View Scheme
参考文献
Vermeulen, Erik S; van Smeden, Marjan; Schmidt, Anne W; Sprouse, Jeffrey S; Wikstroem, Hakan V; Grol, Cor J
Journal of medicinal chemistry, 2004 , vol. 47, # 22 p. 5451 - 5466
反应条件
potassium carbonate in acetonitrile
T=50°C;
参考文献
Vermeulen, Erik S; van Smeden, Marjan; Schmidt, Anne W; Sprouse, Jeffrey S; Wikstroem, Hakan V; Grol, Cor J
Journal of medicinal chemistry, 2004 , vol. 47, # 22 p. 5451 - 5466