3-氯-6-肼基-4,5-二氮杂三环[6.2.2(2,7)]十二碳-2(7),3,5-三烯合成路线 （共 2 条）
反应条件
hydrazine hydrate in ethanol
18 h; Heating;
参考文献
Russell, Michael G. N.; Carling, Robert W.; Atack, John R.; Bromidge, Frances A.; Cook, Susan M.; Hunt, Peter; Isted, Catherine; Lucas, Matt; McKernan, Ruth M.; Mitchinson, Andrew; Moore, Kevin W.; Narquizian, Robert; Macaulay, Alison J.; Thomas, David; Thompson, Sally-Anne; Wafford, Keith A.; Castro, Jose L.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 5 p. 1367 - 1383
反应条件
1: 90 percent / POCl3 / 14 h / Heating
2: 74 percent / NH2NH2*H2O / ethanol / 18 h / Heating
View Scheme
参考文献
Russell, Michael G. N.; Carling, Robert W.; Atack, John R.; Bromidge, Frances A.; Cook, Susan M.; Hunt, Peter; Isted, Catherine; Lucas, Matt; McKernan, Ruth M.; Mitchinson, Andrew; Moore, Kevin W.; Narquizian, Robert; Macaulay, Alison J.; Thomas, David; Thompson, Sally-Anne; Wafford, Keith A.; Castro, Jose L.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 5 p. 1367 - 1383
