(-)-文斯内酯合成路线

151907-79-8(-)-(1S,4R)-N-叔丁氧羰基-4-氨基环戊-2-烯-1-甲酸

参考文献

Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

79200-56-9(-)-文斯内酯

1312161-65-1+

151907-79-8(-)-(1S,4R)-N-叔丁氧羰基-4-氨基环戊-2-烯-1-甲酸+

298716-03-7(1R,4R)-4-(Boc-氨基)-2-环戊烯羧酸

参考文献

DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; LLOYD, Richard; PETERSON, Justine, Ann; JACKSON, Mark
Patent: WO2011/3061 A2, 2011 ;

79200-56-9(-)-文斯内酯

229614-55-5帕拉米韦

参考文献

Jia, Fei; Hong, Juan; Sun, Ping-Hua; Chen, Jian-Xin; Chen, Wei-Min
Synthetic Communications, 2013 , vol. 43, # 19 p. 2641 - 2647

79200-56-9(-)-文斯内酯

168683-02-14-[[(1,1-二甲基乙氧基)羰基]氨基]-2-环戊烯-1-羧酸甲酯

参考文献

Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

79200-56-9(-)-文斯内酯

168960-18-7[(1R,4S)-4-(羟基甲基)-2-环戊烯-1-基]-氨基甲酸叔丁酯

参考文献

Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A.
Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 1-2 p. 297 - 327

24424-99-5二碳酸二叔丁酯+

79200-56-9(-)-文斯内酯

151792-53-92-甲基-2-丙基(1R,4S)-3-氧代-2-氮杂双环[2.2.1]庚-5-烯-2-羧酸酯

参考文献

GLENMARK PHARMACEUTICALS LTD.
Patent: WO2005/75426 A1, 2005 ;
Location in patent: Page/Page column 29-30 ;
WO 2005/075426 A1

79200-56-9(-)-文斯内酯

625108-11-43-氨基环戊烷羧酸甲酯

参考文献

MERCK and CO., INC.
Patent: WO2004/92124 A2, 2004 ;
Location in patent: Page 48 ;
WO 2004/092124 A2