1-(4-溴-2-氰基苯基)哌嗪合成路线 （共 2 条）
反应条件
hydrogenchloride
T=20°C; 0.25 h;
参考文献
Matulenko, Mark A.; Surber, Bruce; Fan, Leimin; Kolasa, Teodozyi; Nakane, Masaki; Terranova, Marc A.; Uchic, Marie E.; Miller, Loan N.; Chang, Renjie; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 20 p. 5095 - 5098
反应条件
1: 62 percent / Et3N / dimethylsulfoxide / 24 h / 90 °C
2: 89 percent / aq. HCl / 0.25 h / 20 °C
View Scheme
参考文献
Matulenko, Mark A.; Surber, Bruce; Fan, Leimin; Kolasa, Teodozyi; Nakane, Masaki; Terranova, Marc A.; Uchic, Marie E.; Miller, Loan N.; Chang, Renjie; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 20 p. 5095 - 5098
