(2E)-3-甲基-5-(四氢-2H-吡喃-2-基氧基)-2-戊烯-1-醇合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in diethyl ether
T=-40°C; 3.25 h;
参考文献
Blaszykowski, Christophe; Harrak, Youssef; Goncalves, Maria-Helena; Cloarec, Jean-Manuel; Dhimane, Anne-Lise; Fensterbank, Louis; Malacria, Max
Organic Letters, 2004 , vol. 6, # 21 p. 3771 - 3774
反应条件
1.1: Na / methanol / 1 h / 0 °C
1.2: 73 percent / methanol / 1.5 h / 0 °C
2.1: CuBr*Me2S / tetrahydrofuran; diethyl ether / 1 h / -78 °C
2.2: tetrahydrofuran; diethyl ether / 4 h / -78 °C
3.1: 5.37 g / LiAlH4 / diethyl ether / 3.25 h / -40 °C
View Scheme
参考文献
Blaszykowski, Christophe; Harrak, Youssef; Goncalves, Maria-Helena; Cloarec, Jean-Manuel; Dhimane, Anne-Lise; Fensterbank, Louis; Malacria, Max
Organic Letters, 2004 , vol. 6, # 21 p. 3771 - 3774
反应条件
1.1: CuBr*Me2S / tetrahydrofuran; diethyl ether / 1 h / -78 °C
1.2: tetrahydrofuran; diethyl ether / 4 h / -78 °C
2.1: 5.37 g / LiAlH4 / diethyl ether / 3.25 h / -40 °C
View Scheme
参考文献
Blaszykowski, Christophe; Harrak, Youssef; Goncalves, Maria-Helena; Cloarec, Jean-Manuel; Dhimane, Anne-Lise; Fensterbank, Louis; Malacria, Max
Organic Letters, 2004 , vol. 6, # 21 p. 3771 - 3774
