(17beta)-雌甾-1,3,5(10),9(11)-四烯-3,17-二醇合成路线 （共 13 条）
反应条件
sodium hydroxide; sodium tetrahydroborate in methanol T=0 - 20°C;
参考文献
Lim, Chongsoo; Evenson, Gerald N.; Perrault, William R.; Pearlman, Bruce A.
Tetrahedron Letters, 2006 , vol. 47, # 36 p. 6417 - 6420
反应条件
potassium hydroxide in methanol T=40°C; 4 h;
参考文献
Schwarz, Sigfrid; Schumacher, Matthias; Nanninga, Anita; Weber, Gisela; Thieme, Ina; Undeutsch, Bernd; Elger, Walter
Steroids, 1999 , vol. 64, # 7 p. 460 - 471
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Chemical and pharmaceutical bulletin, , vol. 11, # 8 p. 1022 - 1027
反应条件
1: Zn, AcOH 2: LiAlH4 / tetrahydrofuran View Scheme
参考文献
Chemical and pharmaceutical bulletin, , vol. 11, # 8 p. 1022 - 1027
反应条件
1: 92.1 percent / Si(0); KF / ethane-1,2-diol; various solvent(s) / 2 h / 140 °C 2: 99.9 percent / NaBH4; NaOH / aq. methanol / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 36 p. 6417 - 6420
反应条件
1: 80 percent / oxone, aq. NaHCO3, TBAHS / CH2Cl2 / 3.5 h / 15 - 20 °C 2: 95 percent / aq. H2SO4 / CH2Cl2 / -30 °C 3: 65 percent / KOH / methanol / 4 h / 40 °C View Scheme
参考文献
Steroids, , vol. 64, # 7 p. 460 - 471
反应条件
1: 95 percent / aq. H2SO4 / CH2Cl2 / -30 °C 2: 65 percent / KOH / methanol / 4 h / 40 °C View Scheme
参考文献
Steroids, , vol. 64, # 7 p. 460 - 471
反应条件
potassium hydroxide in methanol
参考文献
Helvetica Chimica Acta, , vol. 55, p. 852 - 873
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Chemical and pharmaceutical bulletin, , vol. 11, # 8 p. 1022 - 1027
反应条件
1: O2, methylene blue / acetone; benzene / Ambient temperature; Irradiation 2: (i) NaBH4, (ii) TsOH View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 1879 - 1882
