methanesulfonyl chloride; sodium iodide 1.) pyridine, 0.5 h, room temperature, 2.) acetone, 0.5 h, reflux; Yield given. Multistep reaction;

sodium hydride in tetrahydrofuran; mineral oil T=0 - 20°C; 2.5 h;

1: 58.2 g / sodium hydride / tetrahydrofuran / 1.) reflux, 5 min, 2.) room temperature, 0.5 h 2: 38.0 g / KOH, H2O / methanol / 1 h 3: 1.) methanesulphonyl chloride, 2.) sodium iodide / 1.) pyridine, 0.5 h, room temperature, 2.) acetone, 0.5 h, reflux View Scheme

1: 55.3 g / AnalaR pyridine / 1 h / Ambient temperature 2: 58.2 g / sodium hydride / tetrahydrofuran / 1.) reflux, 5 min, 2.) room temperature, 0.5 h 3: 38.0 g / KOH, H2O / methanol / 1 h 4: 1.) methanesulphonyl chloride, 2.) sodium iodide / 1.) pyridine, 0.5 h, room temperature, 2.) acetone, 0.5 h, reflux View Scheme

1: 38.0 g / KOH, H2O / methanol / 1 h 2: 1.) methanesulphonyl chloride, 2.) sodium iodide / 1.) pyridine, 0.5 h, room temperature, 2.) acetone, 0.5 h, reflux View Scheme