1,4-环己二酮-2,5-二甲酸二乙酯合成路线 （共 61 条）
反应条件
sodium hydride in ethylene glycol dimethyl ether T=60°C; Dieckmann reaction; 15 h;
参考文献
Lemouchi, Cyprien; Vogelsberg, Cortnie S.; Zorina, Leokadiya; Simonov, Sergey; Batail, Patrick; Brown, Stuart; Garcia-Garibay, Miguel A.
Journal of the American Chemical Society, 2011 , vol. 133, # 16 p. 6371 - 6379
反应条件
sodium acetate in N,N-dimethyl-formamide 2 h;
参考文献
Vereshchagin, A. L.; Semenov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 1549
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 8 p. 1772 - 1773
反应条件
1: 2-amino-4-lt;(cyclohexylmethyl)aminogt;pyrimidin-6-one With sodium acetate in water; N,N-dimethyl-formamide 0.166667 h; Inert atmosphere; 2: ethyl alpha-chloroacetoacetate in water; N,N-dimethyl-formamide 126 h; Inert atmosphere;
参考文献
Kuykendall, Darrell W.; Anderson, Cyrus A.; Zimmerman, Steven C.
Organic Letters, 2009 , vol. 11, # 1 p. 61 - 64
反应条件
potassium carbonate; 18-crown-6 ether in diethyl ether 24 h; Ambient temperature;
参考文献
Pelter, Andrew; Al-Bayati, Redha I. H.; Ayoub, Miqdad T.; Lewis, Wynn; Pardasani, Pushpa; Hansel, Rudolf
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 717 - 742
反应条件
potassium carbonate in acetone 3 h; Heating;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
反应条件
potassium carbonate in acetone 1.25 h; Heating;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
反应条件
potassium carbonate in acetone 3.5 h; Heating;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
反应条件
potassium fluoride in methanol 22 h; Heating;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
反应条件
potassium fluoride in methanol T=20°C; 192 h;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
反应条件
potassium carbonate in acetone 6 h; Heating;
参考文献
Lamotte, Genevieve; Demerseman, Pierre; Royer, Rene
Synthesis, 1984 , # 12 p. 1068 - 1070
