2,5-二氯吡啶-3-羰酰氯合成路线 （共 6 条）
反应条件
thionyl chloride in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 18 p. 2676 - 2688
反应条件
1: sodium hypochlorite, 50percent aq. NaOH / Ambient temperature 2: SOCl2 / dimethylformamide / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 18 p. 2676 - 2688
反应条件
thionyl chloride 1 h; Heating;
参考文献
Journal of Chemical & Engineering Data, , vol. 26, # 3 p. 332 - 333
参考文献
Sankyo Company, Limited
Patent: US5965591 A1, 1999 ;
反应条件
in benzene 1 h; Heating; Yield given;
参考文献
ASTRAZENECA AB
Patent: WO2006/25783 A1, 2006 ;
Location in patent: Page/Page column 71 ;
WO 2006/025783 A1
反应条件
1: pyridine / dioxane; cyclohexane / Heating 2: xylene / Heating 3: NaH / various solvent(s) / Heating 4: 1.) NaH / 1.) DMSO, 2.) DMSO View Scheme
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
