2-联苯-4-喹啉-4-羧酸合成路线 （共 7 条）
反应条件
1: With sodium hydroxide Heating; 2: With acetic acid 0.5 h;
参考文献
Saudi, Manal N. S.; Rostom, Sherif A. F.; Fahmy, Hesham T. Y.; El Ashmawy, Ibrahim M.
Archiv der Pharmazie, 2003 , vol. 336, # 3 p. 165 - 174
反应条件
potassium hydroxide in water T=20°C; Suzuki-Miyaura cross-coupling reaction; 20 h;
参考文献
Beletskaya, Irina P.; Kashin, Alexander N.; Khotina, Irina A.; Khokhlov, Alexey R.
Synlett, 2008 , # 10 p. 1547 - 1552
反应条件
sulfuric acid in acetic acid 20 h; Heating;
参考文献
Belen'kaya, R. S.; Boreko, E. I.; Zemtsova, M. N.; Kalinina, M. I.; Timofeeva, M. M.; et al.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 3 p. 171 - 176
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 3 p. 29 - 35
反应条件
1: 32 percent / conc. aq. NH3 / ethanol / 24 h / Ambient temperature 2: 57 percent / conc. aq. H2SO4 / acetic acid / 20 h / Heating View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 15, # 3 p. 171 - 176
Khimiko-Farmatsevticheskii Zhurnal, , vol. 15, # 3 p. 29 - 35
反应条件
1: 32 percent / conc. aq. NH3 / ethanol / 24 h / Ambient temperature 2: 57 percent / conc. aq. H2SO4 / acetic acid / 20 h / Heating View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 15, # 3 p. 171 - 176
Khimiko-Farmatsevticheskii Zhurnal, , vol. 15, # 3 p. 29 - 35
反应条件
1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 2.5 h / 85 °C 2: sulfuric acid / 60 - 90 °C 3: potassium hydroxide / ethanol / 72.5 h / |Reflux View Scheme
参考文献
Letters in Drug Design and Discovery, , vol. 10, # 5 p. 420 - 426
反应条件
1: sulfuric acid / 60 - 90 °C 2: potassium hydroxide / ethanol / 72.5 h / |Reflux View Scheme
参考文献
Letters in Drug Design and Discovery, , vol. 10, # 5 p. 420 - 426
