3-溴-6-甲氧基-2-甲基苯胺合成路线 （共 4 条）
反应条件
iron; ammonium chloride in ethanol; water
1.16667 h; HeatingReflux;
参考文献
WYETH
Patent: WO2009/111260 A1, 2009 ;
Location in patent: Page/Page column 35-36 ;
WO 2009/111260 A1
反应条件
1: 160.5 g / Br2 / acetic acid; CHCl3 / 2 h
2: 81.2 g / NaOH / H2O / Heating
3: iron fillings / benzene / Heating
View Scheme
参考文献
Cannon; Lukszo; Max
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 1 p. 149 - 153
反应条件
1: 81.2 g / NaOH / H2O / Heating
2: iron fillings / benzene / Heating
View Scheme
参考文献
Cannon; Lukszo; Max
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 1 p. 149 - 153
反应条件
1: With acetic anhydride in chloroform
T=0 - 20°C;
2: With potassium acetate; isopentyl nitrite in chloroform
20 h; Reflux;
参考文献
WYETH
Patent: WO2009/111260 A1, 2009 ;
Location in patent: Page/Page column 36 ;
WO 2009/111260 A1
