3,4-二氨基噻吩二氢溴酸盐合成路线 （共 32 条）
反应条件
[Cu2(bpnp)(OH)(CF3COO)3]; tetrabutylammomium bromide; ammonia; caesium carbonate in ethylene glycol T=140°C; 16 h; Sealed tube; chemoselective reaction;
参考文献
Liao, Bei-Sih; Liu, Shiuh-Tzung
Catalysis Communications, 2013 , vol. 32, p. 28 - 31
反应条件
1: With hydrogenchloride; tin in water T=0 - 20°C; 12 h; 2: With potassium hydroxide in water pH=7 - 8;
参考文献
Wen, Li; Nietfeld, Jon P.; Amb, Chad M.; Rasmussen, Seth C.
Journal of Organic Chemistry, 2008 , vol. 73, # 21 p. 8529 - 8536
反应条件
water; sodium carbonate
参考文献
Kuraray Co., Ltd.; Kondou, Yoshirou; Nakano, Kirihiro; Otake, Tomiaki
Patent: US8519150 B2, 2013 ;
Location in patent: Page/Page column 33; 34 ;
反应条件
in xylene 0.5 h; Heating;
参考文献
Chimirri, Alba; Gitto, Rosaria; Grasso, Silvana; Romeo, Giovanni; Zappala, Maria
Heterocycles, 1992 , vol. 34, # 6 p. 1191 - 1200
反应条件
sodium carbonate in water T=20°C; 1 h;
参考文献
Kenning, Don D.; Mitchell, Kari A.; Calhoun, Tessa R.; Funfar, Melanie R.; Sattler, Daniel J.; Rasmussen, Seth C.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 9073 - 9076
反应条件
sodium hydrogencarbonate in ethanol; ethyl acetate
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5463073 A1, 1995 ;
US 5463073 A
反应条件
pyridinium p-toluenesulfonate in ethanol
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US5215994 A1, 1993 ;
US 5215994 A
反应条件
in ethanol T=20°C; 3 h;
参考文献
Kenning, Don D.; Mitchell, Kari A.; Calhoun, Tessa R.; Funfar, Melanie R.; Sattler, Daniel J.; Rasmussen, Seth C.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 9073 - 9076
反应条件
in ethanol
T=20°C; 3 h;
参考文献
Kenning, Don D.; Mitchell, Kari A.; Calhoun, Tessa R.; Funfar, Melanie R.; Sattler, Daniel J.; Rasmussen, Seth C.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 9073 - 9076
反应条件
water; sodium hydrogencarbonate
参考文献
Motoyama et al.
Nippon Kagaku Zasshi, 1957 , vol. 78, p. 779,783
Chem.Abstr., 1960 , p. 22559
