1-苄基哌嗪-2-酮盐酸盐合成路线 （共 6 条）
反应条件
hydrogenchloride in 1,4-dioxane
参考文献
Haley, Gregory Jay; Kong, Norman; Liu, Emily Aijun; Simonsen, Klaus B.; Vu, Binh Thanh; Webber, Stephen Evan
Patent: US2004/259884 A1, 2004 ;
Location in patent: Page 13 ;
反应条件
1,2-diamino-benzene in ethanol 2 h; Heating;
参考文献
Tsizin, Yu.S.; Sergovskaya, N.L.; Chernyak, S.A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 4 p. 421 - 424
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 4 p. 514 - 517
反应条件
1: 35 percent / potassium tert-butylate / 2-methyl-propan-2-ol / 0.33 h / Ambient temperature 2: 60 percent / o-phenylendiamine / aq. ethanol / 2 h / Heating View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 22, # 4 p. 421 - 424
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 22, # 4 p. 514 - 517
反应条件
1: 92 percent / Na2CO3 / CH2Cl2 / 0.67 h / 0 °C 2: 35 percent / potassium tert-butylate / 2-methyl-propan-2-ol / 0.33 h / Ambient temperature 3: 60 percent / o-phenylendiamine / aq. ethanol / 2 h / Heating View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 22, # 4 p. 421 - 424
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 22, # 4 p. 514 - 517
反应条件
triethylamine in chloroform T=20°C; 1 h;
参考文献
Tsizin, Yu.S.; Sergovskaya, N.L.; Chernyak, S.A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 4 p. 421 - 424
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 4 p. 514 - 517
反应条件
in ethyl acetate; benzene
参考文献
The Upjohn Company
Patent: US4251438 A1, 1981 ;
