3-(苯并[d][1,3]二氧代-5-基)-1-丙胺合成路线 （共 5 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=-5 - 20°C; 0.5 h;
参考文献
Kalypsys, Inc.
Patent: US2006/116515 A1, 2006 ;
Location in patent: Page/Page column 58 ;
US 20060116515 A1
反应条件
Pd-C in sodium hydroxide; water
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: EP525360 A2, 1993 ;
反应条件
ammonium hydroxide; sodium hypochlorite in water
1.) 0 deg C, 5-10 min, 2.) 0 deg C -> room temperature;
参考文献
Kabalka, George W.; Wang, Zhe; Goudgaon, Nganna M.
Synthetic Communications, 1989 , vol. 19, # 13-14 p. 2409 - 2414
反应条件
ammonium hydroxide; sodium hypochlorite; borane-THF
1.) THF, 0 deg C to r.t., 1 h, 2.) 0 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kabalka, George W.; Sastry, Kunda A. R.; McCollum, Gary W.; Yoshioka, Hiroaki
Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4296 - 4298
反应条件
methanol; borane-THF; trimethylsilylazide
1.) reflux, 2.) reflux, 40 h; Yield given. Multistep reaction;
参考文献
Kabalka, George W.; Goudgaon, Naganna M.; Liang, Yanhong
Synthetic Communications, 1988 , vol. 18, # 12 p. 1363 - 1370
