5-(2-氨基乙基)-1-氮杂双环[3.3.0]辛烷合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in diethyl ether
2.) 20percent NaOH/H2O;
参考文献
Miyano; Shima; Hayashimatsu; Satoh; Sumoto
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 5 p. 416 - 418
反应条件
1: 54.9 percent / aq. NH3 / hexane / 40 h / 15 °C
2: 63 percent / H2, NaOH / Rany-Ni / methanol / 24 h / 20 - 25 °C
View Scheme
参考文献
Suzuki, Tomoo; Usui, Toshinao; Oka, Mitsuru; Suzuki, Tsunemasa; Kataoka, Tadashi
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 8 p. 1265 - 1273
反应条件
1: 65 percent / dioxane / Heating
2: 84 percent / LiAlH4
View Scheme
参考文献
Miyano, Seiji; Yamashita, Osamu; Fujii, Shinichiro; Somehara, Takao; Sumoto, Kunihiro
Heterocycles, 1981 , vol. 16, # 5 p. 755 - 758
