2-苯基巯基苯并吡喃-4-酮合成路线 （共 59 条）
反应条件
1: piperidine / toluene
2: formic acid
3: toluene
View Scheme
参考文献
Taylor, A. W.; Dean, D. K.
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1845 - 1848
反应条件
1: formic acid
2: toluene
View Scheme
参考文献
Taylor, A. W.; Dean, D. K.
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1845 - 1848
反应条件
1: 96 percent / NaH / tetrahydrofuran / 1 h / 60 °C
2: 68 percent / tetrahydrofuran / 1 h / Ambient temperature
3: piperidine / toluene
4: formic acid
5: toluene
View Scheme
参考文献
Taylor, A. W.; Dean, D. K.
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1845 - 1848
反应条件
1: 96 percent / NaH / tetrahydrofuran / 1 h / 60 °C
2: 68 percent / tetrahydrofuran / 1 h / Ambient temperature
3: piperidine / toluene
4: formic acid
5: toluene
View Scheme
参考文献
Taylor, A. W.; Dean, D. K.
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1845 - 1848
反应条件
1: aq. KOH / 0.5 h / 0 - 20 °C
2: 89 percent / toluene / 8 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Rao, Ashok T.; Pandey, Bipin
Journal of the Chemical Society, Chemical Communications, 1992 , # 21 p. 1580 - 1581
反应条件
1: aq. KOH / 0.5 h / 0 - 20 °C
2: 89 percent / toluene / 8 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Rao, Ashok T.; Pandey, Bipin
Journal of the Chemical Society, Chemical Communications, 1992 , # 21 p. 1580 - 1581
反应条件
1: triethylamine / dichloromethane / 0.5 h / 0 °C
2: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -15 - 0 °C / Inert atmosphere
3: sulfuric acid / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Lee, Jae In; Kim, Min Jung
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 4 p. 1383 - 1386
反应条件
1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -15 - 0 °C / Inert atmosphere
2: sulfuric acid / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Lee, Jae In; Kim, Min Jung
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 4 p. 1383 - 1386
反应条件
1: sodium hydroxide / ethanol; water / 20 h / 0 - 20 °C
2: iodine; sodium hydrogencarbonate / 1-methyl-pyrrolidin-2-one / 4 h / Reflux
View Scheme
参考文献
Kobayashi, Kazuhiro; Kobayashi, Akihiro; Ezaki, Kosuke
Heterocycles, 2012 , vol. 85, # 8 p. 1997 - 2004
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
1.2: 1 h / 0 °C
2.1: sodium hydroxide / ethanol; water / 20 h / 0 - 20 °C
3.1: iodine; sodium hydrogencarbonate / 1-methyl-pyrrolidin-2-one / 4 h / Reflux
View Scheme
参考文献
Kobayashi, Kazuhiro; Kobayashi, Akihiro; Ezaki, Kosuke
Heterocycles, 2012 , vol. 85, # 8 p. 1997 - 2004
