2-苯基巯基苯并吡喃-4-酮合成路线 （共 59 条）
反应条件
PPA(phosphoric pentaoxide
T=90°C; 1 h;
参考文献
Nakazumi; Watanabe; Kitaguchi; Kitao
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 3 p. 847 - 851
反应条件
acetic anhydride; toluene-4-sulfonic acid
24 h; Heating;
参考文献
Somogyi
Canadian Journal of Chemistry, 2001 , vol. 79, # 7 p. 1159 - 1165
反应条件
1: aq. KOH / 0.5 h / 20 °C
2: imidazole / CH2Cl2 / 0 - 20 °C
3: 90 percent / tetrahydrofuran / 18 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
反应条件
iodine in dimethyl sulfoxide
T=150°C; 12 h; Overall yield = 73 percent; regioselective reaction;
参考文献
Zheng, Gang; Ma, Xiaoli; Liu, Bangyu; Dong, Ying; Wang, Mang
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 4 p. 743 - 748
反应条件
PPA(phosphoric pentaoxide
T=20 - 30°C; 1 h;
参考文献
Nakazumi; Watanabe; Kitaguchi; Kitao
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 3 p. 847 - 851
反应条件
potassium hydroxide; [bis(acetoxy)iodo]benzene in methanol
72 h; Ambient temperature; Further byproducts given;
参考文献
Somogyi
Synthetic Communications, 1999 , vol. 29, # 11 p. 1857 - 1872
反应条件
1: imidazole / CH2Cl2 / 0 - 20 °C
2: 90 percent / tetrahydrofuran / 18 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
反应条件
1: cuprous iodide, dichlorobis(triphenylphosphine)palladium(II) / triethylamine / 6 h / 60 °C
2: HBr / acetic acid / 2 h / Heating
View Scheme
参考文献
Luxen, Andre J.; Christiaens, Leon E. E.; Renson, Marcel J.
Journal of Organometallic Chemistry, 1985 , vol. 287, p. 81 - 86
反应条件
1: cuprous iodide, dichlorobis(triphenylphosphine)palladium(II) / triethylamine / 6 h / 60 °C
2: HBr / acetic acid / 2 h / Heating
View Scheme
参考文献
Luxen, Andre J.; Christiaens, Leon E. E.; Renson, Marcel J.
Journal of Organometallic Chemistry, 1985 , vol. 287, p. 81 - 86
反应条件
1: 68 percent / tetrahydrofuran / 1 h / Ambient temperature
2: piperidine / toluene
3: formic acid
4: toluene
View Scheme
参考文献
Taylor, A. W.; Dean, D. K.
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1845 - 1848
