2,3,4,5,6-五氟联苯合成路线 （共 79 条）
反应条件
sodium iodide in acetonitrile T=24°C; further reagents; various arenes; effect of benzene concentration; Product distributionMechanism;
参考文献
Journal of the American Chemical Society, , vol. 119, # 21 p. 4846 - 4855
反应条件
potassium tert-butylate; tetrabutylammomium bromide in tetrahydrofuran; water T=50°C; Suzuki coupling; 24 h;
参考文献
Bandari, Rajendar; Hoeche, Thomas; Prager, Andrea; Dimberger, Klaus; Buchmeiser, Michael R.
Chemistry - A European Journal, 2010 , vol. 16, # 15 p. 4650 - 4658
反应条件
palladium diacetate; acetic acid T=75°C; 12 h; Inert atmosphereIonic liquid;
参考文献
Tetrahedron Letters, , vol. 52, # 42 p. 5525 - 5529
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; potassium carbonate in toluene; tert-butyl alcohol T=120°C; 17 h; Inert atmosphereMicrowave irradiation;
参考文献
Chang, Joyce Wei Wei; Chia, Eugene Yurong; Chai, Christina Li Lin; Seayad, Jayasree
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 11 p. 2289 - 2299
反应条件
lithium iodide in THF-d8 (tetrahydrofuran-d8) T=20°C; 0.0833333 h; Inert atmosphereGlovebox;
参考文献
Ohashi, Masato; Doi, Ryohei; Ogoshi, Sensuke
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 2040 - 2048
反应条件
potassium tert-butylate; tetrabutylammomium bromide in tetrahydrofuran; water T=50°C; Suzuki-type cross-coupling reaction; 24 h;
参考文献
Proch; Mei; Rivera Villanueva; Lu; Karpov; Ballauff; Kempe
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 3 p. 493 - 500
反应条件
potassium tert-butylate; tetrabutylammomium bromide in tetrahydrofuran; water T=50°C; Suzuki-type cross-coupling reaction; 24 h;
参考文献
Proch; Mei; Rivera Villanueva; Lu; Karpov; Ballauff; Kempe
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 3 p. 493 - 500
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium hydroxide in tetrahydrofuran; water T=70°C; Suzuki coupling; 7 h; Inert atmosphere;
参考文献
Chen, Chao; Kehr, Gerald; Froehlich, Roland; Erker, Gerhard
Journal of the American Chemical Society, 2010 , vol. 132, # 39 p. 13594 - 13595
反应条件
1: With potassium phosphate in isopropyl alcohol T=20°C; Suzuki coupling; 2 h; Inert atmosphere; 2: With Bophos in isopropyl alcohol T=20°C; Suzuki coupling; 20 h; Inert atmosphere;
参考文献
Organometallics, , vol. 31, # 4 p. 1329 - 1334
反应条件
dichlorotris(triphenylphosphine)ruthenium(II) T=240°C; 24 h;
参考文献
Kamigata, Nobumasa; Yoshikawa, Manabu; Shimizu, Toshio
Journal of Fluorine Chemistry, 1998 , vol. 87, # 1 p. 91 - 95
