2,3,4,5,6-五氟联苯合成路线 （共 79 条）
反应条件
methylethyl sulfide; palladium diacetate; acetic acid; silver carbonate T=120°C; 20 h; Inert atmosphere;
参考文献
Li, Hu; Liu, Jia; Sun, Chang-Liang; Li, Bi-Jie; Shi, Zhang-Jie
Organic Letters, 2011 , vol. 13, # 2 p. 276 - 279
反应条件
potassium phosphate; chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium(II); 2,2,2-trimethylacetic acid in N,N-dimethyl acetamide T=80°C; Glovebox;
参考文献
Zhang, Hong-Hai; Dong, Jie; Hu, Qiao-Sheng
European Journal of Organic Chemistry, 2014 , vol. 2014, # 6 p. 1327 - 1332
反应条件
Pd(OH)2/Fe3O4; sodium carbonate in toluene T=130°C; Suzuki-Miyaura reaction; 48 h;
参考文献
Cano, Rafael; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 2011 , vol. 67, # 30 p. 5432 - 5436
反应条件
tri-tert-butyl phosphine; palladium diacetate; potassium carbonate; silver(l) oxide in toluene T=100°C; 8 h; Inert atmosphere; Reagent/catalyst;
参考文献
Shabalin, Anton Yu.; Adonin, Nicolay Y.; Bardin, Vadim V.; Parmon, Valentin N.
Tetrahedron, 2014 , vol. 70, # 23 p. 3720 - 3725
反应条件
potassium phosphate; copper(l) iodide; 1,10-phenanthroline; tetra-(n-butyl)ammonium iodide in dimethyl sulfoxide; acetonitrile T=130°C; 4 h; Inert atmosphereSchlenk technique;
参考文献
Zhu, Xingyi; Li, Feng; Su, Weike
Tetrahedron Letters, 2013 , vol. 54, # 10 p. 1285 - 1289
反应条件
Ag2CO3; oxygen; palladium diacetate in dimethyl sulfoxide T=130°C; Sealed tube;
参考文献
Luo, Hai-Qing; Dong, Wen; Loh, Teck-Peng
Tetrahedron Letters, 2013 , vol. 54, # 22 p. 2833 - 2836
反应条件
palladium diacetate; silver(l) oxide in 1-methyl-pyrrolidin-2-one T=100°C; 15 h; GloveboxSchlenk technique;
参考文献
Fang, Xin; Huang, Yuanyuan; Chen, Xiaoqing; Lin, Xiaoxi; Bai, Zhengshuai; Huang, Kuo-Wei; Yuan, Yaofeng; Weng, Zhiqiang
Journal of Fluorine Chemistry, 2013 , vol. 151, p. 50 - 57
反应条件
palladium diacetate; potassium carbonate; silver(l) oxide; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene T=100°C; 8 h; Inert atmosphere; Reagent/catalyst;
参考文献
Shabalin, Anton Yu.; Adonin, Nicolay Y.; Bardin, Vadim V.; Parmon, Valentin N.
Tetrahedron, 2014 , vol. 70, # 23 p. 3720 - 3725
反应条件
palladium diacetate; tri-cyclo-hexyl-phosphine in diethylene glycol dimethyl ether T=130°C; 24 h; Inert atmosphereSealed tube;
参考文献
Shang, Rui; Xu, Qing; Jiang, Yuan-Ye; Wang, Yan; Liu, Lei
Organic Letters, 2010 , vol. 12, # 5 p. 1000 - 1003
反应条件
tri-tert-butyl phosphine; cesium fluoride; silver(l) oxide; tris-(dibenzylideneacetone)dipalladium(0) in N,N-dimethyl-formamide T=100°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Korenaga, Toshinobu; Kosaki, Takahiro; Fukumura, Rokki; Ema, Tadashi; Sakai, Takashi
Organic Letters, 2005 , vol. 7, # 22 p. 4915 - 4917
