3-甲氧基-5-乙酰基氨基苯甲酸合成路线 （共 3 条）
反应条件
1: HCl (d 1.17) / 0.5 h 2: 1) 20percent aq. NaOH, 98percent hydrazine hydrate, Raney nickel / 1) water, 70 to 75 deg. C; 2) 70 to 80 deg. C, 30 min View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, # 2 p. 313 - 317
Zhurnal Organicheskoi Khimii, , vol. 17, # 2 p. 369 - 374
反应条件
sodium hydroxide; nickel; hydrazine hydrate 1) water, 70 to 75 deg. C; 2) 70 to 80 deg. C, 30 min; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, # 2 p. 313 - 317
Zhurnal Organicheskoi Khimii, , vol. 17, # 2 p. 369 - 374
反应条件
1: 72.5 percent / H2SO4 (d 1.83), HNO3 (d 1.51) / 0.5 h / 0 - 8 °C
2: 94 percent / Ba(OH)2 * 8H2O / H2O / heating on a boiling water bath
3: 1) H2SO4, NaNO2; 2) Cu2Br2, HBr / 1) water, 0 to 5 deg. C, 30 min
4: 89.5 percent / diethyl ether
View Scheme
参考文献
Nekhoroshev, A. A.; Sevbo, D. P.; Ginzburg, O. A.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, # 2 p. 313 - 317
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 2 p. 369 - 374
