2-甲基-1-丁烯-3-炔合成路线 （共 145 条）
反应条件
1: 2-methyl-1-butene-3-yne With n-butyllithium; potassium tert-butylate in tetrahydrofuran; hexane
T=-78 - 5°C; 0.666667 h;
2: 4-bromo-but-1-ene With lithium bromide in tetrahydrofuran; hexane
T=-70 - -10°C;
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
1: 2-methyl-1-butene-3-yne With n-butyllithium; potassium tert-butylate in tetrahydrofuran; hexane
T=-78 - 5°C; 0.666667 h;
2: 3-bromo-1-(trimethylsilyl)-1-propyne With lithium bromide in tetrahydrofuran; hexane
T=-70 - -10°C;
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
1: 2-methyl-1-butene-3-yne With n-butyllithium; potassium tert-butylate in tetrahydrofuran; hexane
T=-78 - 5°C; 0.666667 h;
2: 2-bromoethoxy-tert-butyldimethylsilane With lithium bromide in tetrahydrofuran; hexane
T=-70 - -10°C;
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
maleic anhydride; dpca in tetrahydrofuran
50°C, 24 h;
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
maleic anhydride; dpca in tetrahydrofuran
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
maleic anhydride; dpca in tetrahydrofuran
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
maleic anhydride; dpca in tetrahydrofuran
50°C, 24 h;
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
maleic anhydride; dpca in tetrahydrofuran
参考文献
Nakao, Yoshiaki; Hirata, Yasuhiro; Ishihara, Shinjiro; Oda, Shinichi; Yukawa, Tomoya; Shirakawa, Eiji; Hiyama, Tamejiro
Journal of the American Chemical Society, 2004 , vol. 126, # 48 p. 15650 - 15651
反应条件
n-butyllithium
1.) THF, hexane, -78 deg C, 30 min, 2.) 1 h; Yield given. Multistep reaction;
参考文献
Moore, Harold W.; West, Kevin F.; Wriede, Ulrich; Chow, Ken; Fernandez, Mario; Nguyen, Nghi V.
Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2537 - 2549
反应条件
2,2'-azo-bisisobutyronitrile; toluene in neat (no solvent)
Kinetics; under N2 at 60-65°C; further products; GC, NMR;
参考文献
Cochran, J. C.; Leusink, A. J.; Noltes, J. G.
Organometallics, 1983 , vol. 2, p. 1099 - 1105
