6,8-二甲氧基-3-甲基异色满-1-酮合成路线 （共 15 条）
反应条件
1: 91 percent / 0.17 h / 140 - 150 °C
2: 70 percent / sodium borohydride / 1 h / Heating
View Scheme
参考文献
Henderson, Graeme B.; Hill, Robert A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1111 - 1116
反应条件
lithium diisopropyl amide
1.) THF, -78 deg C, 30 min, 2.) -78 deg C; Yield given. Multistep reaction;
参考文献
Carpenter, T. Adrian; Evans, Geoffrey E.; Leeper, Finian J.; Staunton, James; Wilkinson, Michael R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 1043 - 1051
反应条件
n-butyllithium
1.) hexane, -78 deg C, 2.) 2 h; Yield given. Multistep reaction;
参考文献
Carpenter, T. Adrian; Evans, Geoffrey E.; Leeper, Finian J.; Staunton, James; Wilkinson, Michael R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 1043 - 1051
反应条件
lithium diisopropyl amide
1.) THF, -78 deg C, 30 min, 2.) -78 deg C, 4 h; Yield given. Multistep reaction;
参考文献
Carpenter, T. Adrian; Evans, Geoffrey E.; Leeper, Finian J.; Staunton, James; Wilkinson, Michael R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 1043 - 1051
反应条件
AlCl3, aluminium chloride in 1,4-dioxane
T=20°C; 15 h; Heating / reflux;
参考文献
NIPRI LIMITED
Patent: WO2006/46071 A1, 2006 ;
Location in patent: Page/Page column 49; 61-62 ;
