2-氨基-3-氯苯甲酸甲酯合成路线 （共 13 条）
反应条件
iron; acetic acid in ethanol T=20°C; 2 h; Heating / reflux;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/259850 A1, 2007 ;
Location in patent: Page/Page column 99 ;
US 20070259850 A1
反应条件
potassium carbonate in methanol
参考文献
Hoechst Aktiengesellschaft
Patent: US5557005 A1, 1996 ;
反应条件
in methanol; ethyl acetate
参考文献
DowElanco
Patent: US5068392 A1, 1991 ;
反应条件
triethylamine in methanol
反应条件
sulfuric acid 28 h; Heating;
参考文献
Arisawa, Mitsuhiro; Terada, Yukiyoshi; Takahashi, Kazuyuki; Nakagawa, Masako; Nishida, Atsushi
Journal of Organic Chemistry, 2006 , vol. 71, # 11 p. 4255 - 4261
反应条件
1: 89 percent / K2CO3 / acetone / 0.5 h / Heating 2: SnCl2*2H2O; conc. HCl / ethanol / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 7, # 8 p. 1743 - 1754
反应条件
N-chloro-succinimide; isopropyl alcohol Chlorination; 0.25 h; Heating; Title compound not separated from byproducts;
参考文献
Synlett, , # 12 p. 1984 - 1986
反应条件
triethylamine in methanol
参考文献
BASF Aktiengesellschaft
Patent: US4306074 A1, 1981 ;
参考文献
BASF Aktiengesellschaft
Patent: US4306074 A1, 1981 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 2.16667 h; 2: With water; sodium sulfate in tetrahydrofuran T=0°C;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/259850 A1, 2007 ;
Location in patent: Page/Page column 99 ;
US 20070259850 A1
