(R)-(-)-2-苯丙酸合成路线 （共 166 条）
反应条件
(-)-(S)-β-Np-BTM; trimethylacetic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Inert atmosphereResolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Onda, Yu-Suke; Itagaki, Makoto
Journal of the American Chemical Society, 2010 , vol. 132, # 33 p. 11629 - 11641
反应条件
sodium hydroxide in water T=40°C; 1.25 h; titrisol buffer pH 8, carboxylesterase NP; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 111, # 11 p. 490 - 495
反应条件
hydrogen cation 22 h; Heating;
参考文献
Beard, Timothy; Cohen, Mark A.; Parratt, Julian S.; Turner, Nicholas J.; Crosby, John; Moilliet, Jock
Tetrahedron: Asymmetry, 1993 , vol. 4, # 6 p. 1085 - 1104
反应条件
1: With hydrogen; CN; palladium on activated charcoal in ethyl acetate 1 h; 2: With sodium hydroxide; bromine in 1,4-dioxane; water 3 h; 3: With sodium sulfite in 1,4-dioxane; water Title compound not separated from byproducts;
参考文献
European Journal of Organic Chemistry, , # 23 p. 3986 - 3994
反应条件
Birman's catalyst; N-ethyl-N,N-diisopropylamine in toluene T=20°C; 10 h; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2301 - 2304
反应条件
Birman's catalyst; benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 35 p. 5887 - 5890
反应条件
Birman's catalyst; benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 11 h; Resolution of racemate; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 35 p. 5887 - 5890
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in toluene T=20°C; 10 h; enantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2301 - 2304
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 24 h; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2301 - 2304
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in toluene T=20°C; 10 h; enantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2301 - 2304
