反应条件
1: 1) n-BuLi, N-isopropylcyclohexylamine / 1) THF, -70 deg C, 1 h, 2) THF, HMPA, r.t., overnight 2: 20percent aq. NaOH / methanol / 2 h / Heating 3: 1) diphenylphosphorazidate, Et3N, 2) 15percent HCl, AcOH / 1) benzene, a) 1 h, b) r.t., 1 h, c) reflux, 3 h, 2) r.t., overnight 4: 60 percent / SO2Cl2, Et3N / diethyl ether / a) -70 deg C, 2 h, b) -20 deg C, overnight 5: 1) NaH, 2) tert-butyl hypochlorite / 1) hexane, r.t., 3 h, 2) hexane, r.t., overnight View Scheme
参考文献
Walborsky, H. M.; Topolski, M.; Hamdouchi, C.; Pankowski, J.
Journal of Organic Chemistry, 1992 , vol. 57, # 23 p. 6188 - 6191
