1: malonic acid ethyl ester monopotassium salt With magnesium chloride in acetonitrile T=35°C; 0.75 h; 2: With triethylamine in acetonitrile T=25°C; 0.5 h; 3: 1-(3-fluorobenzoyl) imidazole With hydrogenchloride; water more than 3 stages;
参考文献
Ouellet, Stephane G.; Gauvreau, Danny; Cameron, Mark; Dolman, Sarah; Campeau, Louis-Charles; Hughes, Gregory; O'Shea, Paul D.; Davies, Ian W.
Organic Process Research and Development, 2012 , vol. 16, # 2 p. 214 - 219