4-甲氧基-N,N-二甲基-苯乙胺合成路线 （共 15 条）
反应条件
hydrogenchloride T=160°C;
参考文献
Epstein,J. et al.
Journal of the American Chemical Society, 1964 , vol. 86, p. 3075 - 3084
反应条件
hydrogen; palladium on activated charcoal in ethanol
T=50°C; P=3750.38 Torr; 10 h;
参考文献
EGIS GYOGYSZERGYAR NYILVANOSAN MUeKOeDOe
Patent: WO2009/144517 A1, 2009 ;
Location in patent: Page/Page column 27-29 ;
反应条件
formic acid in water
3 h; Heating;
参考文献
Schroeder, Daniel R.; Stermitz, Frank R.
Tetrahedron, 1985 , vol. 41, # 19 p. 4309 - 4320
反应条件
in tetrahydrofuran
T=20°C; 18 h;
参考文献
Woscholski, Rudiger; Hailes, Helen; Numbere, Macba; Rosivatz, Erika
Patent: US2009/221702 A1, 2009 ;
Location in patent: Page/Page column 11 ;
反应条件
methanol; palladium
Hydrogenation;
参考文献
Kindler; Hesse
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 439,445
Show Details
Buck; Baltzly; Ide
Journal of the American Chemical Society, 1938 , vol. 60, p. 1789,1790
参考文献
Yoon, Seung Soo; Oei, Yoko; Sweet, Elizabeth; Schultz, Peter G.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11686 - 11687
反应条件
1: ethyl (3-dimethylaminopropyl)dicarbodiimide
2: borane-THF complex
View Scheme
参考文献
Yoon, Seung Soo; Oei, Yoko; Sweet, Elizabeth; Schultz, Peter G.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11686 - 11687
反应条件
cesium fluoride in N,N,N',N',N'',N''-hexamethylphosphoric triamide
5 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tanaka, Tetsuya; Shirai, Naohiro; Sugimori, Junji; Sato, Yoshiro
Journal of Organic Chemistry, 1992 , vol. 57, # 18 p. 5034 - 5036
反应条件
in methanol
Ambient temperature;
参考文献
Katsu; Ono; Tasaka; Fujita
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4185 - 4188
反应条件
hydrogenchloride
T=20°C; elektrolytische Reduktion an Bleikathode;
参考文献
Kindler
Archiv der Pharmazie (Weinheim, Germany), 1927 , p. 390,400
Chem. Zentralbl., 1924 , vol. 95, # II p. 1404
