1: 100 percent / 25percent aq. NaOH / methanol / 2 h / Ambient temperature 2: 1.) 5 M aq. HCl / 1.) RT, 90 min, 2.) pH = 5.5, RT, 4 h 3: conc. HCl / methanol / 40 h / 60 - 70 °C / pH = 5.5 View Scheme

1: 100 percent / 25percent aq. NaOH / methanol / 2 h / Ambient temperature 2: 1.) 5 M aq. HCl / 1.) RT, 90 min, 2.) pH = 5.5, RT, 4 h 3: NaBH3CN / 1.17 h View Scheme

1: 100 percent / 25percent aq. NaOH / methanol / 2 h / Ambient temperature 2: 1.) 5 M aq. HCl / 1.) RT, 90 min, 2.) pH = 5.5, RT, 4 h 3: 16 h / Ambient temperature 4: 8 M HCl / 13 h / 100 - 110 °C View Scheme