2-氨基甲酰基-3-硝基苯甲酸合成路线 （共 22 条）
参考文献
Chapman; Stephen
Journal of the Chemical Society, 1925 , vol. 127, p. 1794
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: SOCl2 / tetrahydrofuran; dimethylformamide / 20 °C 3: conc. aq. NH3 / tetrahydrofuran; dimethylformamide 4: H2 / 10percent Pd/C / methanol / 760.05 Torr View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 60 percent / HCl(g) / 6 h / Heating View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 66 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr 3: 44 percent / Cu(OAc)2 / methanol; H2O / Heating View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 60 percent / HCl(g) / 6 h / Heating 3: 64 percent / Et3N / tetrahydrofuran / 12 h / 20 °C 4: 75 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 60 percent / HCl(g) / 6 h / Heating 3: 94 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: sodium hypochlorite; water; sodium hydroxide / 0 - 80 °C 2: hydrazine hydrate; sodium hydroxide / methanol / Reflux 3: N,N-dimethyl-formamide / 120 h / 80 °C View Scheme
参考文献
Xue, Fei; Luo, Xianjin; Ye, Chenghao; Ye, Weidong; Wang, Yue
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 8 p. 2641 - 2649
反应条件
1: aq. KOH; Br2 / 80 °C 2: NaOH; hydrazine hydrate; Raney Ni 3: K3Fe(CN)6 / methanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 2 p. 267 - 269
反应条件
1: aq. KOH; Br2 / 80 °C 2: NaOH; hydrazine hydrate; Raney Ni 3: K3Fe(CN)6 / methanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 2 p. 267 - 269
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 66 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr 3: 48 percent / Cu(OAc)2 / methanol; H2O / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 22 p. 4084 - 4097
