1.1: n-BuLi / tetrahydrofuran; hexane / 1.5 h / -78 °C 1.2: tetrahydrofuran; hexane 2.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -60 °C 2.2: tetrahydrofuran; hexane / -60 - 20 °C View Scheme

n-butyllithium; magnesium bromide 1) diethyl ether, -78 deg C, 5 min, 2) warmed to RT; Yield given. Multistep reaction;

1: 2-Bromo-trans-stilbene Oxide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1.5 h; 2: methyl iodide in tetrahydrofuran; hexane

n-butyllithium; magnesium bromide 1) THF, hexane, -78 deg C, 5 min, 2) ether and warmed to RT; Yield given. Multistep reaction;