(R)-(+)-2-氯丙酸甲酯合成路线 (共 9 条)
反应条件
poly{N-[(1S,2S)-2-benzyloxycyclopentyl]maleimide} Resolution of racemate;
参考文献
EP1479669 A1, ;
Page 12; 13 ;
反应条件
aluminium trichloride in dichloromethane T=40°C; 24 h;
参考文献
Azzena, Ugo; Delogu, Giovanna; Melloni, Giovanni; Piccolo, Oreste
Tetrahedron Letters, 1989 , vol. 30, # 34 p. 4555 - 4558
反应条件
in methanol; hexane; toluene 0.0833333 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 126, # 15 p. 4790 - 4791
反应条件
Zymomonas mobilis nicotinamide-dependent cyclohexanone reductase; NADH T=30°C; pH=7.5; 24 h; aq. bufferEnzymatic reaction; stereoselective reaction;
参考文献
Chemistry - A European Journal, , vol. 18, # 33 p. 10362 - 10367
反应条件
Saccharomyces cerevisiae Old Yellow Enzyme 3 ene-reductase; NADH T=30°C; pH=7.5; 24 h; aq. bufferEnzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Chemistry - A European Journal, , vol. 18, # 33 p. 10362 - 10367
参考文献
Chemische Berichte, , vol. 28, p. 1295,1296
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 30, p. 535,538
反应条件
T=20°C; 2 h; Inert atmosphere;
参考文献
EP2532646 A1, ;
Page/Page column 7-8 ;
反应条件
HMG-Cl T=70°C; Product distribution; Further Variations:TemperaturesReagents;
参考文献
Violleau, Frederic; Thiebaud-Roux, Sophie; Borredon, Elisabeth; Le Gars, Pierre
Tetrahedron, 2002 , vol. 58, # 42 p. 8607 - 8612
反应条件
subtilisin in water T=30°C; Kinetics;
参考文献
Liu, Andrew Man Fai; Somers, Neil A.; Kazlauskas, Romas J.; Brush, Terry S.; Zocher, Frank; Enzelberger, Markus M.; Bornscheuer, Uwe T.; Horsman, Geoff P.; Mezzetti, Alessandra; Schmidt-Dannert, Claudia; Schmid, Rolf D.
Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 545 - 556