叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯合成路线

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/107923 A1, 2006 ;
Location in patent: Page/Page column 66 ;

103-76-41-(2-羟乙基)哌嗪+

34619-03-9

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Hoffmann-La Roche Inc.; Hermann, Johannes Cornelius; Kuglstatter, Andreas; Lucas, Matthew C.; Padilla, Fernando; Wanner, Jutta; Zhang, Xiaohu
Patent: US2013/109661 A1, 2013 ;
Location in patent: Paragraph 0620-0621 ;

540-51-22-溴乙醇+

57260-71-61-Boc-哌嗪

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Hill, Pamela J.; Abibi, Ayome; Albert, Robert; Andrews, Beth; Gagnon, Moriah M.; Gao, Ning; Grebe, Tyler; Hajec, Laurel I.; Huang, Jian; Livchak, Stephania; Lahiri, Sushmita D.; McKinney, David C.; Thresher, Jason; Wang, Hongming; Olivier, Nelson; Buurman, Ed T.
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245435-42-1

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Honda, Toshio; Ishikawa, Fumihiro
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103-76-41-(2-羟乙基)哌嗪+

89985-91-12-甲基-2-丙基2-吡啶基碳酸酯

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Bulletin of the Korean Chemical Society, , vol. 33, # 5 p. 1547 - 1550

34619-03-9

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Bulletin of the Korean Chemical Society, , vol. 33, # 9 p. 2971 - 2975

103-76-41-(2-羟乙基)哌嗪+

1426682-55-4

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

参考文献

Bulletin of the Korean Chemical Society, , vol. 33, # 9 p. 2971 - 2975

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

655225-01-74-(2-溴乙基)-1-哌嗪羧酸-1,1-二甲基乙酯

参考文献

DAC SRL; AMICI, Raffaella; COLOMBO, Andrea; COURTNEY, Stephen Martin; MERCURIO, Ciro; MONTALBETTI, Christian Aldo Georges Napoleon; MORTONI, Annalisa; VARASI, Mario
Patent: WO2013/64919 A1, 2013 ;
Location in patent: Page/Page column 37; 38 ;

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

103-76-41-(2-羟乙基)哌嗪

参考文献

WO2012/48259 A2, ;

Page/Page column 41 ;
WO 2012/048259 A2

77279-24-4叔丁基-4-(2-羟乙基)哌嗪-1-羧酸酯

208167-83-34-(2-氯乙基)四氢-1(2H)-吡嗪羧酸叔丁酯

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/107923 A1, 2006 ;
Location in patent: Page/Page column 65-66 ;