6-氨基-2-苯并噻唑甲腈合成路线 （共 10 条）
反应条件
in dimethyl sulfoxide T=120°C;
参考文献
The University of Tokyo
Patent: US2007/155806 A1, 2007 ;
Location in patent: Page/Page column 5 ;
反应条件
stannous chloride; sodium hydrogencarbonate in ethanol
反应条件
in dimethyl sulfoxide T=120°C; Inert atmosphere;
参考文献
Takakura, Hideo; Kojima, Ryosuke; Urano, Yasuteru; Terai, Takuya; Hanaoka, Kenjiro; Nagano, Tetsuo
Chemistry - An Asian Journal, 2011 , vol. 6, # 7 p. 1800 - 1810
反应条件
1: sulfuric acid; potassium nitrate / 1.5 h / 0 - 20 °C 2: hydrogenchloride; tin(ll) chloride / ethanol; water / 120 °C 3: dimethyl sulfoxide / 120 °C / Inert atmosphere View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 6, # 7 p. 1800 - 1810
反应条件
1: hydrogenchloride; tin(ll) chloride / ethanol; water / 120 °C 2: dimethyl sulfoxide / 120 °C / Inert atmosphere View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 6, # 7 p. 1800 - 1810
反应条件
1.1: potassium nitrate; sulfuric acid / 1 h / 10 - 40 °C 2.1: ammonia / methanol / 20 °C 3.1: pyridine; trichlorophosphate / 2.33 h / 0 - 20 °C / Inert atmosphere 3.2: 0 °C 4.1: tin(ll) chloride / ethanol / 2 h / 60 °C / Inert atmosphere 4.2: pH 7 View Scheme
反应条件
1.1: nitric acid; sulfuric acid / 0 - 25 °C 2.1: pyridine; trichlorophosphate / 2.33 h / 0 - 20 °C / Inert atmosphere 2.2: 0 °C 3.1: tin(ll) chloride / ethanol / 2 h / 60 °C / Inert atmosphere 3.2: pH 7 View Scheme
反应条件
1.1: iron sulphate heptahydrate; sulfuric acid; dihydrogen peroxide / water / 0.5 h / 0 °C 1.2: pH 6 / Cooling with ice 2.1: ammonia / methanol / 20 °C 3.1: pyridine; trichlorophosphate / 2.33 h / 0 - 20 °C / Inert atmosphere 3.2: 0 °C 4.1: tin(ll) chloride / ethanol / 2 h / 60 °C / Inert atmosphere 4.2: pH 7 View Scheme
反应条件
1.1: nitric acid; sulfuric acid / 2.75 h / 0 °C 2.1: tin(ll) chloride / ethanol / 2 h / 60 °C / Inert atmosphere 2.2: pH 7 View Scheme
反应条件
(i) NaNH2, liq. NH3, (ii) /BRN= 1567902/, MeOH; Multistep reaction;
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1966 , vol. 88, p. 2015 - 2019
